Si loola dagaallamo jeermiska cudurada fangas, daawooyin badan ayaa la soo saaraa maanta. Dhaqtarkana dhakhtarkaba waxaa ku jira doorasho adag oo ah daawada ugu fiican ee tan ama kiiskan.
Kiniiniyada ketoconazole ama diyaargarasyo kale oo ku salaysan waa wakiilada antifungal ee ficil fara badan. Waxay ka caawiyaan in lagu daaweeyo jimicsiga nidaamsan, taas oo ah, cudurrada ay sababaan fangaska, iyo sidoo kale infekshannada fangas-maskaxda ah - mycoses, seborrhea.
Ketoconazole wuxuu leeyahay saameyn waxyeello u leh miro-sida fangaska caanaha caanaha, dermatophytes, fangaska caaga, cudurada kala duwan ee malaksiga nidaamka iyo xitaa staphylococci iyo streptococci.
Goormaa Ketoconazole Kiniinada Kiniiniga Kale?
Tilmaamaha isticmaalka ketoconazole waa:
- infakshanka fungal ee habka dheef-shiidka;
- infakshanka fungal ee xubnaha unugyada kaadida-xubnahiisa, oo ay ku jiraan shahwada siilka, oo si fiican loo yaqaanno cayayaanka, iyo sidoo kale kiniiniga xinjirowga ah ee joogtada ah;
- mashiinka ciddiyaha, maqaarka, timo, paronychia, folliculitis;
- dermatiga xayawaanka (xayawaan);
- fungal septicaemia;
- indhaha miisaanka;
- miyir-mareenka nidaamsan - xakameyn, blastomycosis, histoplasmosis, iwm;
- ka hortagga faafka fungal ee dadka qaba difaaca jirka iyo khatarta sii kordheysa ee dhaawacyada fungal.
Marka la qaato hadal ahaan, daawooyinka ketoconazole ee kiniinada ayaa bixiya daaweyn wax ku ool ah oo loogu talagalay maaddada dusha sare iyo nidaamyada. Tallaabada walaxdani waxay la xiriirtaa burburinta geedi socodka biosynthesis ee fosfolipids ergosterol iyo triglycerides, kuwaas oo ku lug leh samaynta mareenka unugyada fungal. Ugu dambeyntii, koritaanka iyo isku dhufashada unugyada waxyeelada leh ayaa joojiya oo cudurkuna soo noqdaa.
Marka la qaato afka, diyaargarowga si fiican ayaa loo nuugay, taas oo ah, oo dhiig ku daatay, oo si ballaaran loogu qaybiyay unugyada, qayb yar ayaa galinaysa dheecaanka cerebrospinal. Ka dib marka la nuugo maadada dheef-shiidka, walaxda firfircooni waa qiyaasta beerka, oo sameysma tiro badan oo ah unugyo aan firfircooneyn. Daawada ayaa ka baxday kaadida (13%), oo ka soo baxday xaydha waxayna ka soo baxday saxarada (57%).
Caadi ahaan 1-2 kiniin ayaa la qaataa maalintii oo cunto ah 2-8 todobaad, taas oo ku xidhan cudurada iyo miisaanka jirka. Daawada ayaa loo maamuli karaa carruurta ka weyn 12 sano.
Contraindications iyo saameynaha ka yimaada qaadashada Ketoconazole
Kiniinada ketoconazole ee ka yimaada dermatitis dermatitis iyo cudurrada kale ee astaamaha fungal waxay ka hortagaan uurka, kalkaalinta, carruurta da'doodu ka yar tahay 12 sano, dadka qaba xanuunka ketoconazole iyo cilladda daran ee kelyaha iyo beerka.
Dhibaatooyinka kale ee qaadashada kiniiniga waa sida soo socota:
- lallabbo iyo matag;
- shubanka;
- Xanuunka hurdada;
- dawakhaad, madax xanuun;
- timo lumis;
- sharaxaadda;
- exanthema;
- rabitaanka galmada oo hoos u dhacday;
- ginecomastia;
- cudurka urtikaria, finanka maqaarka;
- photophobia;
- qandho
Maamulidda afka ah ee diyaarinta ketoconazole waa inay la socotaa kormeer caafimaad oo joogto ah: tijaabooyinka dhiigga, hubinta beerka iyo hawlaha kelyaha. Waxaa iska cad in la isdifaaco iyo is-daaweynta is-daaweyntan. Daaweynta waxaa kaliya oo qori kara dhakhtar.
Xaaladda mininjaytis fungal ah, isticmaalka ketoconazole laguma talin karo, maadaama maaddadu aanay si fiican ugu dhex gelin BBB (barxadda hemato-encephalic).
Diyaargarasyo ku salaysan walxadan waa hepatotoksik, sidaa daraadeed habka kaliya waa in la isticmaalaa marka faa'idada ka iman karta khatarta suurtagalka ah. Gaar ahaan waxay ku saabsan tahay bukaannada qaba xanuun badan oo ka mid ah firfircoonida sare ee cayayaanka hepatitis-ka ama ay waxyeelo u geysato beerka sababta oo ah qaadashada daawooyinka kale.
Diyaarinta ketoconazole ee kiniinnada
Halkan waxaa ku qoran magacyada qaabdhismeedka qaabka ketoconazole ee kiniinnada (sida ku cad qaybta firfircoon):
- Mycosorrhal;
- Fungistab;
- Dermazol;
- Oronazole;
- Nizoor ;
- KetoconazoleAltapharm;
- Ketoconazole DS;
- Mikanisal;
- Livarol;
- Mikoket;
- Fungin.