Qanjirrada adrenal waxay soo saaraan 17-OH-progesterone , taas oo haweenka ka masuul ah hannaanka hoormoonka ee wareegga caadada. Heerkeeduna ma ahan mid joogta ah oo isbeddelaya inta lagu jiro wareegga: wuxuu hoos u dhacayaa ka hor inta aan la ogaanin, kor u kaco oo uu ku sarreyso qeybta dambe ee wareegga. Haddii uusan uur lahayn, markaa bilowga wareegga xiga, heerka 17-OH-progesterone ayaa hoos u dhacaya.
Sababaha sii kordhaya 17-OH-progesterone
Uurka waa mid ka mid ah sababaha 17-OH-progesterone uu sarreeyo . Hore ka dib marka la isku miiro iyo la geliyo, heerka hoormoonkan ayaa bilaabmaya inuu kaco.
Haddii aysan jirin uur, markaas waxaa jira sababo kale, taas oo ay sabab u tahay 17-oh-progesterone, cudurada sida adrenal ama burooyinka ugxan-sidaha, adrenal hyperplasia ee ku dhasha.
Calaamadaha sii kordhaya 17-OH-progesterone
Caadi ahaan, heerka 17-OH-progesterone:
- ragga laga bilaabo 0.2 ilaa 2.3 ng / ml;
- ee haweenka wajiga hore ee wareegga laga bilaabo 0.2 ilaa 1.2 ng / ml;
- labaad - laga bilaabo 1.0 ilaa 4.5 ng / ml;
- marka uurku ka jiro 2,0 ilaa 12,0 ng / ml.
Waxaa suurtagal ah in laga shakiyo kororka heerka 17-OH-progesterone ee haweenka leh muuqaalka koritaanka timaha ee xad-dhaafka ah ee jidhka iyo khafiifinta. Kordhinta heerka hoormoonka waxay keenaysaa caadooyin aan caadi ahayn haweeney ama amenorrhea dhammeystiran. Sidoo kale, kororka 17-OH-progesterone wuxuu keenaa dhibaatooyinka xubnaha iyo nidaamyada kale:
- Heerarka sonkorta dhiigga waxay kordhayaan;
- waxaa jira dhibaatooyin maqaar iyo finan;
- cadaadiska dhiigga oo kor u kaca iyo kolestaroolka;
- waxaa jira kala goynta hawsha wadnaha haweeney da 'kasta.
Daaweynta kordhinta 17-OH-progesterone
Si loo saxo hormoonka suuxdinta ka dib marka la ogaado heerka uu ku jiro dhiigga daawada hormoonada hormoonada (Prednisolone, Dexamethasone). Koorsada daaweyntu waxay qaadataa illaa lix bilood, joojinta daaweynta looma qaban karo si lama filaan ah: qiyaasta qiyaasta hoormoonka waxaa mar walba hagaajiya dhakhtarka.